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Journal Club

Our global experts summarize key findings from the latest clinical trials in a half-hour weekly virtual presentation and panel discussion. Our insights help viewers integrate the latest information into their clinical practice in this constantly evolving field.

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Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Disease (the EPIC-CAD trial)

In patients with atrial fibrillation and stable coronary artery disease, edoxaban monotherapy led to a lower risk of a composite of death from any cause, myocardial infarction, stroke, systemic embolism,…
October 5, 2024 Read More

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Transcatheter Repair vs. Mitral Valve Surgery for Secondary Mitral Regurgitation (the MATTERHORN trial)

September 28, 2024

Transcatheter Valve Repair in Heart Failure with Moderate to Severe Regurgitation (the RESHAPE-HF2 trial)

Among patients with heart failure with moderate to severe functional mitral regurgitation who received medical therapy, the addition of transcatheter mitral-valve repair led to a lower rate of first or…
September 21, 2024

ORBITA-STAR trial and the ORBITA II Symptoms Analysis

In stable coronary artery disease, 30% to 60% of patients remain symptomatic despite successful revascularization. Perhaps not all symptoms reported by a patient with myocardial ischemia are, in fact, angina.…
August 17, 2024

Ischemic Cardiomyopathy – Does Revascularization Still Play a Role?

Each week, we present a journal club in which we choose a study that we believe will be of interest to the interventional cardiology community and discuss it at a…
July 20, 2024

Preventive PCI vs. Optimal Medical Therapy Alone for the Treatment of Vulnerable Atherosclerotic Plaques

The PREVENT trial was designed to compare preventive percutaneous coronary intervention (PCI) plus optimal medical therapy (OMT) with OMT alone in patients with functionally non-significant high-risk vulnerable plaques. Each week,…
July 13, 2024

Microaxial Flow Pump or Standard Care in Infarct-Related Cardiogenic Shock

The effects of temporary mechanical circulatory support with a microaxial flow pump on mortality among patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock remains unclear. Each week,…
July 6, 2024

Self-Expanding or Balloon-Expandable TAVR in Patients with a Small Aortic Annulus

Patients with severe aortic stenosis and a small aortic annulus are at risk for impaired valvular hemodynamic performance and associated adverse cardiovascular clinical outcomes after transcatheter aortic-valve replacement (TAVR). Each…
June 29, 2024

OCT-Based Functional Stenosis Assessment: FUSION

Celebrating the 100th Episode of OPCI's Journal Club!  With deepest gratitude to our illustrious colleagues from around the globe who have graciously joined as presenters and panelists over the years.
June 22, 2024

Coronary Sinus Reducer for the Treatment of Refractory Angina: A Randomised, Placebo-Controlled Trial

The coronary sinus reducer (CSR) is proposed to reduce angina in patients with stable coronary artery disease by improving myocardial perfusion. We aimed to measure its efficacy, compared with placebo,…
June 8, 2024

CT-Guided PCI/P4

Computed tomography (CT) has become an established tool in the diagnostic workup of patients with suspected coronary artery disease (CAD). The availability of coronary CT angiography (CCTA) before the invasive…
May 25, 2024